Myocardial relaxation: effects of preload on the time course of isovolumetric relaxation.

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LABORATORY INVESTIGATION VENTRICULAR PERFORMANCE Myocardial relaxation: effects of preload on the time course of isovolumetric relaxation

We studied the effect of an isolated increase in preload on isovolumetric relaxation in the intact dog heart and isometric relaxation in isolated cardiac muscle (dog and rat) preparations. In eight anesthetized dogs, 8 to 12 ml of blood was infused into the left ventricle during a single diastole. The exponential time constant (T) of isovolumetric relaxation was measured in single-beat experime...

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VENTRICULAR PERFORMANCE Myocardial relaxation : effects of preload on the time course of isovolumetric relaxation

We studied the effect of an isolated increase in preload on isovolumetric relaxation in the intact dog heart and isometric relaxation in isolated cardiac muscle (dog and rat) preparations. In eight anesthetized dogs, 8 to 12 ml of blood was infused into the left ventricle during a single diastole. The exponential time constant (T) of isovolumetric relaxation was measured in single-beat experime...

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Myocardial relaxation: effects of preload on the time course of isovolumetric relaxation.

We studied the effect of an isolated increase in preload on isovolumetric relaxation in the intact dog heart and isometric relaxation in isolated cardiac muscle (dog and rat) preparations. In eight anesthetized dogs, 8 to 12 ml of blood was infused into the left ventricle during a single diastole. The exponential time constant (T) of isovolumetric relaxation was measured in single-beat experime...

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ژورنال

عنوان ژورنال: Circulation

سال: 1986

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.73.5.1037